An approved drug normally used to treat fungal infections could also do the job of a protein channel that is missing or defective in the lungs of people with cystic fibrosis, operating as a prosthesis on the molecular scale.
The Carle Illinois College of Medicine is seeking submissions for the first Illinois Health Make-a-Thon competition. Anyone who lives in Champaign County can submit an idea for improving human health on the Health Maker Lab website. The deadline for idea submissions is March 11. The competition submission form includes three questions: — “What is the […]
Growing muscle tissue on grooved platforms helps neurons more effectively integrate with the muscle, a requirement for engineering muscle in the lab that responds and functions like muscle in the body, University of Illinois researchers found in a new study. Such engineered muscle with integrated nerves has applications in reconstructive and rehabilitative medicine, as well […]
A University of Illinois team of researchers led by chemistry professor and Carle Illinois research mentor M. Christina White has developed a new manganese-based catalyst that can change the structure of druglike molecules to make new drugs, advancing the pace and efficiency of drug development.
By enticing away the repressors dampening unexpressed, silent genes in Streptomyces bacteria, researchers at the University of Illinois have unlocked several large gene clusters for new natural products, according to a study published in the journal Nature Chemical Biology. Since many antibiotics, anti-cancer agents and other drugs have been derived from genes readily expressed in […]
A new compound that targets a receptor within sarcoma cancer cells shrank tumors and hampered their ability to spread in mice and pigs, a study from researchers at the University of Illinois reports. The researchers conducted a multi-year, cross-disciplinary study that went from screening potential drug candidates to identifying and synthesizing one compound, to packaging […]
Researchers developed a rapid sensing gel to measure a molecular marker of eye injury in a teardrop.
In a new study in cells, University of Illinois researchers have adapted CRISPR gene-editing technology to cause the cell’s internal machinery to skip over a small portion of a gene when transcribing it into a template for protein building. This gives researchers a way not only to eliminate a mutated gene sequence, but to influence […]
University of Illinois researchers developed a molecular probe that can tag and track elusive cancer stem cells in both cell cultures and live organisms.
Ask Ruby Mendenhall about the scope of her activities, and you’re quickly overwhelmed. Ask her to illustrate how they all connect, and you’ll soon have a page full of circles, lines, themes and projects – many of them connecting people you’d think would have little to talk about. Yet they do.