May 6, 2019

Mechanics, chemistry and biomedical research join forces for noninvasive tissue therapy

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The new findings show that high-intensity focused ultrasound waves can penetrate biological tissue to activate molecules able to perform specific tasks.

April 30, 2019

Injections, exercise promote muscle regrowth after atrophy in mice, study finds

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By injecting cells that support blood vessel growth into muscles depleted by inactivity, researchers say they are able to help restore muscle mass lost as a result of immobility. The research, conducted in adult mice, involved injections of cells called pericytes (PERRY-sites), which are known to promote blood vessel growth and dilation in tissues throughout […]

molecular prosthetic, Marty Burke, Carle Illinois College of Medicine, University of Illinois at Urbana-Champaign
March 13, 2019

Potential new cystic fibrosis treatment uses ‘molecular prosthetic’ for missing lung protein

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An approved drug normally used to treat fungal infections could also do the job of a protein channel that is missing or defective in the lungs of people with cystic fibrosis, operating as a prosthesis on the molecular scale.

February 25, 2019

Carle Illinois holds first Health Make-a-thon competition

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The Carle Illinois College of Medicine is seeking submissions for the first Illinois Health Make-a-Thon competition. Anyone who lives in Champaign County can submit an idea for improving human health on the Health Maker Lab website. The deadline for idea submissions is March 11. The competition submission form includes three questions: — “What is the […]

January 24, 2019

Feeling groovy: Neurons integrate better with muscle grown on grooved platforms

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Growing muscle tissue on grooved platforms helps neurons more effectively integrate with the muscle, a requirement for engineering muscle in the lab that responds and functions like muscle in the body, University of Illinois researchers found in a new study. Such engineered muscle with integrated nerves has applications in reconstructive and rehabilitative medicine, as well […]

M. Christina White, Carle Illinois College of Medicine, University of Illinois at Urbana-Champaign
January 10, 2019

Researchers diversify drug development options with new metal catalyst

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A University of Illinois team of researchers led by chemistry professor and Carle Illinois research mentor M. Christina White has developed a new manganese-based catalyst that can change the structure of druglike molecules to make new drugs, advancing the pace and efficiency of drug development.

January 3, 2019

Unmuting large silent genes lets bacteria produce new molecules, potential drug candidates

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By enticing away the repressors dampening unexpressed, silent genes in Streptomyces bacteria, researchers at the University of Illinois have unlocked several large gene clusters for new natural products, according to a study published in the journal Nature Chemical Biology. Since many antibiotics, anti-cancer agents and other drugs have been derived from genes readily expressed in […]

December 19, 2018

New drug seeks receptors in sarcoma cells, attacks tumors in animal trials

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A new compound that targets a receptor within sarcoma cancer cells shrank tumors and hampered their ability to spread in mice and pigs, a study from researchers at the University of Illinois reports. The researchers conducted a multi-year, cross-disciplinary study that went from screening potential drug candidates to identifying and synthesizing one compound, to packaging […]

Leanne Labriola, Dipanjan Pan, Ketan Dighe, Carle Illinois College of Medicine, University of Illinois at Urbana-Champaign
August 31, 2018

Color-changing sensor detects signs of eye damage in tears

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Researchers developed a rapid sensing gel to measure a molecular marker of eye injury in a teardrop.

New CRSPR Technique, Carle Illinois College of Medicine, University of Illinois at Urbana-Champaign
August 16, 2018

New CRISPR technique skips over portions of genes that can cause disease

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In a new study in cells, University of Illinois researchers have adapted CRISPR gene-editing technology to cause the cell’s internal machinery to skip over a small portion of a gene when transcribing it into a template for protein building. This gives researchers a way not only to eliminate a mutated gene sequence, but to influence […]