December 10, 2020

Study of non-COVID-19 deaths shows 2020 increase in several demographics

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CHAMPAIGN, Ill. — March through May saw a significant increase in deaths over previous years – and not just from COVID-19, says a new study from the University of Illinois at Urbana-Champaign. When deaths attributed to COVID-19 were removed from the Centers for Disease Control and Prevention totals, the death rate in several demographics outpaced the same period in 2019, the study found. The timeframe represents the first three months of response to the COVID-19 […]

May 6, 2020

Nanostimulators boost stem cells for muscle repair

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CHAMPAIGN, Ill. — In regenerative medicine, an ideal treatment for patients whose muscles are damaged from lack of oxygen would be to invigorate them with an injection of their own stem cells. In a new study published in the journal ACS Nano, researchers at the University of Illinois at Urbana-Champaign demonstrated that “nanostimulators” – nanoparticles seeded with a molecule the body naturally produces to prompt stem cells to heal wounds – can amp up stem […]

April 30, 2020

Spinal cord gives bio-bots walking rhythm

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CHAMPAIGN, Ill. — Miniature biological robots are making greater strides than ever, thanks to the spinal cord directing their steps. University of Illinois at Urbana-Champaign researchers developed the tiny walking “spinobots,” powered by rat muscle and spinal cord tissue on a soft, 3D-printed hydrogel skeleton. While previous generations of biological robots, or bio-bots, could move forward by simple muscle contraction, the integration of the spinal cord gives them a more natural walking rhythm, said study […]

March 2, 2020

Study maps landmarks of peripheral artery disease to guide treatment development

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Carle Illinois College of Medicine professor and research mentor, Huimin Zhao, has developed CRISPR-based technology that “knocks out” yeast genes with single-point precision – offering potential benefits to industries that use the yeast to produce ethanol, chemicals, lubricants and pharmaceuticals.

Illinois researchers demonstrated a CRISPR gene-editing technique that slowed the progression of ALS in mice. Pictured, from left: graduate student Colin Lim, professor Thomas Gaj, graduate student Michael Gapinske, professor Pablo Perez-Pinera.
February 25, 2020

New CRISPR base-editing technology slows ALS progression in mice

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CHAMPAIGN, Ill. — With a new CRISPR gene-editing methodology, scientists from the University of Illinois at Urbana-Champaign inactivated one of the genes responsible for an inherited form of amyotrophic lateral sclerosis – a debilitating and fatal neurological disease for which there is no cure. The novel treatment slowed disease progression, improved muscle function and extended lifespan in mice with an aggressive form of ALS. “ALS unfortunately has few treatment options. This is an important first […]

September 13, 2019

Brad Sutton recognized as one of five University Scholars

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From helping to develop the innovative curricula at Carle Illinois, to his work developing novel MRI methods to help better understand the brain, the honor is well deserved.

May 6, 2019

Mechanics, chemistry and biomedical research join forces for noninvasive tissue therapy

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The new findings show that high-intensity focused ultrasound waves can penetrate biological tissue to activate molecules able to perform specific tasks.

April 30, 2019

Injections, exercise promote muscle regrowth after atrophy in mice, study finds

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By injecting cells that support blood vessel growth into muscles depleted by inactivity, researchers say they are able to help restore muscle mass lost as a result of immobility. The research, conducted in adult mice, involved injections of cells called pericytes (PERRY-sites), which are known to promote blood vessel growth and dilation in tissues throughout the body. The injections occurred at the end of a two-week period during which the mice were prevented from contracting […]

molecular prosthetic, Marty Burke, Carle Illinois College of Medicine, University of Illinois at Urbana-Champaign
March 13, 2019

Potential new cystic fibrosis treatment uses ‘molecular prosthetic’ for missing lung protein

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An approved drug normally used to treat fungal infections could also do the job of a protein channel that is missing or defective in the lungs of people with cystic fibrosis, operating as a prosthesis on the molecular scale.

February 25, 2019

Carle Illinois holds first Health Make-a-thon competition

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The Carle Illinois College of Medicine is seeking submissions for the first Illinois Health Make-a-Thon competition. Anyone who lives in Champaign County can submit an idea for improving human health on the Health Maker Lab website. The deadline for idea submissions is March 11. The competition submission form includes three questions: — “What is the health-related problem you want to address?” — “What is your idea for solving this problem?” — “How will your solution […]