A University of Illinois team of researchers led by chemistry professor and Carle Illinois research mentor M. Christina White has developed a new manganese-based catalyst that can change the structure of druglike molecules to make new drugs, advancing the pace and efficiency of drug development.
By enticing away the repressors dampening unexpressed, silent genes in Streptomyces bacteria, researchers at the University of Illinois have unlocked several large gene clusters for new natural products, according to a study published in the journal Nature Chemical Biology. Since many antibiotics, anti-cancer agents and other drugs have been derived from genes readily expressed in […]
A new compound that targets a receptor within sarcoma cancer cells shrank tumors and hampered their ability to spread in mice and pigs, a study from researchers at the University of Illinois reports. The researchers conducted a multi-year, cross-disciplinary study that went from screening potential drug candidates to identifying and synthesizing one compound, to packaging […]
Researchers developed a rapid sensing gel to measure a molecular marker of eye injury in a teardrop.
In a new study in cells, University of Illinois researchers have adapted CRISPR gene-editing technology to cause the cell’s internal machinery to skip over a small portion of a gene when transcribing it into a template for protein building. This gives researchers a way not only to eliminate a mutated gene sequence, but to influence […]
University of Illinois researchers developed a molecular probe that can tag and track elusive cancer stem cells in both cell cultures and live organisms.
Ask Ruby Mendenhall about the scope of her activities, and you’re quickly overwhelmed. Ask her to illustrate how they all connect, and you’ll soon have a page full of circles, lines, themes and projects – many of them connecting people you’d think would have little to talk about. Yet they do.
A class of molecules formed when the body metabolizes omega-3 fatty acids could inhibit cancer’s growth and spread, University of Illinois researchers report in a new study in mice. The molecules, called endocannabinoids, are made naturally by the body and have similar properties to cannabinoids found in marijuana – but without the psychotropic effects. In […]
The Carle Illinois College of Medicine, the world’s first engineering-based medical school, welcomed its first class of 32 students July 2. A partnership between the University of Illinois at Urbana-Champaign and the Carle Health System, the college aims to create a cohort of physician-innovators who exemplify the qualities of compassion, competence, curiosity and creativity. The […]
A new microscope system can image living tissue in real time and in molecular detail, without any chemicals or dyes, report researchers at the University of Illinois. The system uses precisely tailored pulses of light to simultaneously image with multiple wavelengths. This enables the researchers to study concurrent processes within cells and tissue, and could […]