July 22, 2021

New approach eradicates breast cancer in mice

  • By Ryann Monahan

A new approach to treating breast cancer kills 95-100% of cancer cells in mouse models of human estrogen-receptor-positive breast cancers and their metastases in bone, brain, liver and lungs. The newly developed drug, called ErSO, quickly shrinks even large tumors to undetectable levels. Led by scientists at the University of Illinois Urbana-Champaign, the research team reports the findings in the journal Science Translational Medicine. “Even when a few breast cancer cells do survive, enabling tumors […]

June 1, 2021

New microscope discovery combines AI to detect disease earlier, improve treatment

  • By Ryann Monahan

A newly developed laser source and microscope are helping researchers better understand and search for biomarkers indicative of cancer and other diseases, offering new promise for early detection and treatment plans. The study, co-authored by Carle Illinois College of Medicine professors Stephen Boppart and Saurabh Sinha, including researchers in Boppart’s Biophotonics Imaging Laboratory at the University of Illinois Urbana-Champaign, was recently published in Cancer Research and featured on the cover. The innovative laser source and […]

May 5, 2021

Mantis shrimp-inspired camera provides second opinion during cancer surgery

  • By Beth Hart

CHAMPAIGN, Ill. — Some of the world’s greatest innovations, such as Leonardo da Vinci’s flying machine, owe their strength and elegance to natural design. Researchers from the University of Illinois Urbana-Champaign have returned their gaze to the natural world to develop a camera inspired by the mantis shrimp that can visualize cancer cells during surgery. A new study led by electrical and computer engineering professor Viktor Gruev details how the new camera works with tumor-targeted drugs to see cancer […]

Saif Lab Research
May 5, 2021

Carle Illinois, CCIL Scientist Develops High-Res Sensors to Investigate Cancer Cell Activity

  • By Beth Hart

Urbana, Ill. – When Carle Illinois College of Medicine professor Taher Saif, a professor of mechanical science and engineering, joined the University of Illinois over two decades ago, he thought he would use his skills to help people – by improving their vehicles and cell phones. But just a few years later, he realized his expertise could be put towards another cause: fighting cancer. Saif spent his early career in applied mathematics, where his lab work focused […]

Drs. Bashir and Smith
May 5, 2021

RESEARCHERS DEVELOP NEW TECHNIQUE TO STUDY “MICROCANCERS” AND SCREEN CANCER-FIGHTING DRUGS

  • By Beth Hart

A team from the University of Illinois Urbana-Champaign’s Grainger College of Engineering and Mayo Clinic have developed a new technique for creating “microcancer” cell cultures. It allows researchers to form hundreds of microcancers in a high-throughput format using a small, microfabricated chip, enabling direct measurement of cell health or response to drugs. It also allows researchers to control the shape of the culture using capillary forces and thus create cultures that more closely resemble in-vivo cells’ three-dimensional […]

Rohit Bhargava and Georgina Cheng at CCIL view images of cancer cells
April 20, 2021

CCIL and Carle Collaborate on Cancer Management Project

  • By Beth Hart

Traditionally, someone in a lab will embed tissue in paraffin, pour dye and view it under a microscope to determine if cancer cells are present. However, researchers in bioengineering and medicine at Carle Health are going further and looking at the microenvironment, or molecular chemistry of the cancer cells to understand cancer progression. By measuring the molecular makeup of cancer cells and their effect on the surrounding cells and tissues, that information can provide insight […]

March 10, 2021

Leading New Directions in Cancer Research: The Unanswered Black Box

  • By Beth Hart

Carle Illinois College of Medicine professor Hyunjoon Kong is leading new research that will interrogate how cell communication influences body, tissue, and pathogen development. The goal is to help other clinicians and researchers better understand cell-to-cell communications. This innovation could change the way that scientists and clinicians administer tests and treatments to cancer patients. Kong, Robert W. Schafer professor of chemical and biomolecular engineering, approaches cancer research from a perspective that integrates cell engineering and […]

February 23, 2021

Illinois and Mayo Clinic Researchers Awarded $2.2M DoD Grant for Breast Cancer Imaging Study

  • By Cancer Center at Illinois

Four in ten* patients screened for breast cancer are at a higher risk of misdiagnosis due to the presence of dense breast tissue. Traditional mammography cannot reliably diagnose the disease in these patients, sometimes even with the help of supplemental screening. Even with these extra tests, approximately 80% of patients are misdiagnosed with false positives, causing undue distress and financial strain. About 40% of women present with denser breast tissue in the United States; and […]

December 9, 2020

Research to Improve Breast Cancer Treatment Receives $2 Million NCI Grant

  • By Carle Illinois College of Medicine

New ultrasound technology research by a Carle Illinois College of Medicine professor could change how fast breast cancer patients find out if their initial chemotherapy is working. Some breast cancer patients wait months to learn if their tumors are responding to initial chemotherapy, but Michael Oelze’s new research could shorten the wait to a week. Professor Oelze and his Canadian research partners were awarded a $2 million grant from the National Cancer Institute to study […]