Zeynep Madak-Erdogan

Associate Professor
Biomedical and Translational Sciences

(217) 300-9063

zmadake2@illinois.edu

359 E R Madigan Laboratory

For More Information

Education

B.S. Bilkent University Ankara, Turkey 1998-2002
Ph.D. University of Illinois,Urbana-Champaign Urbana, IL, USA 2004-2009

Research Interests

Role of novel synthetic and natural estrogens on metabolic health of post-menopausal women Keywords: Obesity, Metabolic Syndrome, Genomic and Non-genomic ER signaling, Genomics, Metabolomics
Understanding molecular basis of breast cancer disparities using multi-scale -OMICs analysis Keywords: Health Disparities, Metabolomics, Breast Cancer, African-American Women, Caucasian Women
Impact of Estrogen Receptor alpha and kinase signaling cross-talk on development and progression of breast cancer Keywords: Breast cancer, ER signaling, Kinase, Genomics, Endocrine Resistance
Integrating -OMICs data from RNA-Seq, ChIP-Seq and Metabolomics experiments to understand the molecular basis of metabolic syndrome and cancer Keywords: Nutrigenomics, Biomarker development, Transcriptomics, Cistromics, Metabolomics, Obesity, Breast cancer, Personalized medicine

Selected Articles in Journals

Smith, B.P., Madak-Erdogan Z., Urban Neighborhood and Residential Factors Associated with Breast Cancer in African American Women: A Systematic Review, in print Hormones and Cancer
Chen KL, Zhao YC, Hieronimy K, Smith BP, Madak-Erdogan Z. Bazedoxifene and conjugated estrogen combination maintains metabolic homeostasis and benefits liver health, PLoS One. 2017 Dec 21;12(12):e0189911. PMID:29267318
Chen KL, Madak-Erdogan Z. Estrogens and female liver health, Steroids, 2017 Nov 1. pii: S0039-128X(17)30195-2. doi: 10.1016/j.steroids.2017.10.015, PMID: 29100781
Chen, K.L.; Madak-Erdogan Z., Estrogens and Microbiome crosstalk in metabolic syndrome, Trends in Endocrinology and Metabolism. 2016 Aug 20, PMID:27553057, Invited Review
Madak-Erdogan Z., Kim SH, Gong P, Zhao YC, Zhang H, Chambliss KL, Carlson KE, Mayne CG, Shaul PW, Korach KS, Katzenellenbogen JA, Katzenellenbogen BS. Design of pathway preferential estrogens that provide beneficial metabolic and vascular effects without stimulating reproductive tissues. Science Signaling 2016 May 24;9(429):ra53. PubMed PMID: 27221711.
Madak-Erdogan, Z.*;, Gong, P., Zhao, YC, Xu, L.; Wrobel, K.U.; Hartman, J., Wang, M. Cam, A. Doerge, D., Khan, I.A., Katzenellenbogen, J.A., Katzenellenbogen, B.S., Helferich, W.G., Dietary licorice root supplementation improves menopause associated metabolic syndrome and provides resiliency to high-fat diet *Corresponding author, Molecular Nutrition and Food Research, 2015 Nov 10
Madak-Erdogan Z, Charn T.H, Jiang Y, Liu E.T., Katzenellenbogen J.A., Katzenellenbogen B.S., Integrative Genomics of Gene and Metabolic Regulation by Estrogen Receptors α and β and Coregulators, , Molecular Systems Biology 2013 Jun 18;9:676, PMID: 23774759

Honors

National Institutes of Health (NIH), Future Research Leader (2017)
National Center for Supercomputing Application, Faculty Fellow (2017)
National Institutes of Health (NIH), Early Career Reviewer Program (2016)
Mary Swartz Young Investigator Award, American Society for Nutrition (2016)
Arnold O. Beckman Award, UIUC (2015 and 2017)
ENDO Early Investigators Award, Endocrine Society (2015)
Women in Endocrinology Young Investigator Award (2011)
NIEHS, Postdoctoral Research Training Program in Endocrine Developmental and Reproductive Toxicology Fellowship (2009-2011)
NIEHS, Predoctoral Research Training Program in Endocrine Developmental and Reproductive Toxicology Fellowship (2008-2009)